Targeted drug delivery to magnetic implants for therapeutic applications

نویسندگان

  • Benjamin B. Yellen
  • Zachary G. Forbes
  • Derek S. Halverson
  • Gregory Fridman
  • Kenneth A. Barbee
  • Michael Chorny
  • Robert Levy
  • Gary Friedman
چکیده

A new method for locally targeted drug delivery is proposed that employs magnetic implants placed directly in the cardiovascular system to attract injected magnetic carriers. Theoretical simulations and experimental results support the assumption that using magnetic implants in combination with externally applied magnetic field will optimize the delivery of magnetic drug to selected sites within a subject. r 2005 Published by Elsevier B.V. PACS: 47.65.+a; 47.85. g; 75.50.Mm; 75.50. y; 75.50.Tt; 75.50.Ww; 87.68.+z; 87.80. y

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تاریخ انتشار 2005